The 21st century has ushered in an era of unprecedented disruption, characterized by technological innovation, climate change, global pandemics, and volatile market dynamics. In this context, traditional top-down leadership models are proving insufficient. This chapter, "Redefining Leadership: Adaptive Management in the Era of Disruption," explores how adaptive leadership and agile management practices are becoming essential tools for organizational success. Drawing on contemporary research and real-world case studies, the chapter delves into how resilient leadership, systems thinking, and change management can equip leaders to respond effectively to evolving challenges. It emphasizes the importance of emotional intelligence, collaborative leadership, and decentralized decision-making in creating flexible, responsive organizations. Special attention is given to the role of digital transformation and data-driven strategies in enhancing adaptability. The chapter also introduces the concept of the VUCA (Volatility, Uncertainty, Complexity, Ambiguity) world, offering frameworks for strategic navigation through uncertainty. It encourages leaders to cultivate learning organizations that embrace innovation, inclusivity, and feedback loops. By redefining leadership through the lens of adaptability and continuous learning, the chapter provides a blueprint for sustainable success in disruptive times.